From the lab to clinic: the patient-centered and tight trinity of investments, R&D and patent control

The presentation aims at highlighting several moments in time important for a patent strategy, during the long period from drug discovery up to market introduction, pricing & reimbursement and ultimately access for patients. Groundbreaking inventions relating to the applicability of a known or new molecule (antibody, small molecule, peptide, oligonucleotide, etc.) for treating or preventing a disease often stem from academic research. 

Securing early though decisive measures to gain control over the further development program therefore lie in the hands of universities and academic hospitals, and their tech transfer / valorization officers. If budget allows, building a sound patenting strategy cannot start early enough. If there is a slightest chance that a relevant patient population might benefit enormously from such future new therapy becoming available to them, first patenting rather then (first) publishing is key. The more since such IP strategy paves the way towards investment-ready opportunities, once relative high capital demand is apparent for conducting the necessary clinical trials. Step-by-step, Barend will guide the audience through the important milestones and events that trigger relevant aspects of designing and executing the optimal IP strategy.

Barend Bouma

Barend Bouma | European Patent Attorney, Associate Partner | NLO

Fortifying IP at NLO as a patent attorney, Barend advises his pharma and life sciences Clients on various IP related issues. He has assisted life science clients in building uo and executing successful IP strategies integrated in the overall business. These strategies for example also can focus on late stage rights based on clinical trial data. In view of this Barend is regularly involved in clinical trial design, due diligence (for example for investors, innovators, M&A) and freedom-to-operate analyses. Barend has previous experience as COO and head of R&D of a Dutch Biotech firm and worked several years at an IP strategy consultancy firm.

Rogier Buijsman

Rogier Buijsman | CEO | Crossfire Oncology  

Rogier Buijsman is Chief Executive Officer of Crossfire Oncology. He has more than 25 years of drug discovery experience. In 1998 he obtained his Ph.D. from the University of Leiden afterwhich he started his career at Organon in the Medicinal Chemistry Dept., where he initiated Organon’s kinase research effort, starting multiple succesful kinase inhibitor programmes. In 2011 he co-founded NTRC, a biotech company based in Oss at the Pivot Park. In 2021, he founded Crossfire Oncology, as a spin-off company of NTRC. Rogier has a broad experience in building and leading efficient research teams and projects.

NLO

About NLO

NLO has a team of 45 IP experts in pharma, life sciences, biotech, medtech, healthcare, nutraceuticals, etc. For intellectual property firm NLO added value for Clients comprises far more than only providing prosecution services. Working with Clients in a long-term partnership aimed at protecting their innovations and delivering added value; that's what drives our experts. We do this by designing, executing and maintaining IP strategies together with the Client, and of course by applying for, obtaining, defending and maintaining intellectual property rights (IP), on a global scale.


About Crossfire Oncology 

Crossfire Oncology B.V. (Crossfire), is a biotech company, based on Pivot Park in Oss, which develops a new type of antibody drug conjugates (ADCs) called Degrader Antibody Conjugates or DACs for short. The degraders Crossfire develops make use of a protein degradation mechanism that is present in all cells and are designed to eliminate kinases that play an important role in cancer. By coupling these degraders to antibodies targeted delivery in cancer cells is ensured. Treatment with DACs is expected to increase the therapeutic efficacy, with limited side effects in cancer patients.

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